A plea for biobanking of all equivocal melanocytic proliferations.

In 2005, in an editorial in the Archives of Dermatology (now JAMADermatology), wemade a plea for a combined diagnostic approach tohistopathologic anddermoscopic evaluation.1 Weconcludedoureditorialwith the followingstatement1 (p211): Histopathology, as every other purelymorphologicmethod, is limited by methodologic drawbacks and sometimes by practitioners’ personal limitations.Todayweareon the edgeofanew biology in histopathology, and one can foresee that our beloved classic morphology will soon be replaced by new technologies. In themeantime, a combinedmorphologic approach linkingdermoscopy and histopathology might be helpful for pathologists to come tomore reliable diagnostic conclusions for patients and their physicians.